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Using
science to simplify life
Rubicon Research constantly scans, analyses and identifies the
need for change and improvement in the existing drug
products and delivery systems. This leads to the creation
and development of new technologies that provide value
enrichment. These are patentable and commercially viable.
Some unique technologies have already emerged out of
this activity, and have been branded for easy identification
and IPR appropriation..
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RubiEnTM
is an innovative technology that increases the
bioavailability of poorly soluble drugs by enhancing
their solubility and the dissolution rate in the
acidic environment. This increase is associated
with reduction in dose, variability and adverse
reactions, rapid onset of action leading to better
patient compliance and favorable therapeutic outcome.
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RubiCoatTM
is an innovative coating technology, which allows
use of waxes as coating agents in the form of
their aqueous dispersion without use of heat or
organic solvents. The technology widens the application
base of waxes and permits their use in pharmaceutical
industry for modified release, taste masking and
drug stabilisation application. |
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RubiRetenTM
is a novel drug delivery system which combines
the concepts of solubilisation and gastroretention
to achieve increased bioavailability of poorly
soluble active having window of absorption. The
delivery system makes the absorbable form of drug
available at the site of absorption and can be
applied to drug molecules belonging to different
therapeutic categories..
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RubiXcipTM
is a novel multifunctional excipient obtained
from fenugreek seeds. It forms highly viscous
dispersions in contact with water, which are comparable
to commercial polymers. The viscosity is independent
of pH, temperature and ionic strength. This relatively
inexpensive excipient can be used for varied applications
in pharmaceutical, food and cosmetic industry. |
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RubiDTTM
attempts to provide benefits of a liquid
suspension with a tablet formulation thereby increasing
compliance for paediatrics and geriatrics. This
tablet formulation when placed in a spoonful of
water, disintegrates to form a suspension with
reduced sedimentation rate, ensuring accuracy
of the dose. |
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RubiODTTM
is a novel orally disintegrating tablet of optimal
strength, which disintegrates in the mouth in
less than 30 seconds. The tablet can be manufactured
using conventional equipments, and is applicable
to various drug substances. This can also be used
in synergy with RubiCoat taste masking technology
for bitter drug substances. |
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RubiERTTM
is an extended release delivery system employing
non-swelling pH dependent and pH independent release
retardant. The technology is flexible and can
be applied for high dose as well as low dose drug
products with varying aqueous solubility. The
non-swelling behavior of the dosage form ensures
that it is independent of food effect. The pH
independence of the dosage form results in reduced
variability. |
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